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« on: February 04, 2010, 02:26:54 AM »

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 Brand name: zelnorm
Generic name: Tegaserod, Zelmac
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The following adverse experiences were reported in 1% or more of patients who received Zelnorm and occurred more frequently than in patients who received placebo. The increase was primarily due to a numerical imbalance in cholecystectomies reported in patients treated with Zelnorm (5/2,965; 0. The effectiveness of Zelnorm in patients 65 years or older with chronic idiopathic constipation has not been established (see Geriatric Use). The majority of the Zelnorm patients reporting diarrhea had a single episode. Zelnorm should be discontinued immediately in patients who develop severe diarrhea, hypotension or syncope.  Zelnorm should be discontinued immediately in patients who develop symptoms of ischemic colitis, such as rectal bleeding, bloody diarrhea or new or worsening abdominal pain.

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